abstract：BACKGROUND:One of recent interesting hypotheses of transient global amnesia (TGA) pathophysiology is the preexisting vulnerability of the memory network in patients with TGA. AIM OF THE STUDY:To verify the hypothesis that patients with recurrent amnestic attacks may have more disrupted structural connectivity than pat...

journal_title：Acta neurologica Scandinavica

authors： Moon Y,Moon WJ,Han SH

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:Orthostatic hypotension (OH) and postural orthostatic tachycardia syndrome (POTS) are well-known causes of orthostatic intolerance (OI). In addition, there are OI patients who are characterized by the symptoms of OI and lack of abnormal findings in head-up tilt (HUT) test. The aim of this study was to determ...

journal_title：Acta neurologica Scandinavica

authors： Shin KJ,Kim SE,Park KM,Park J,Ha SY,Kim SE,Kwon OY

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Excessive daytime sleepiness (EDS) is a symptom frequently presented in sleep clinics. Only a paucity of data has addressed clinical courses of sleep disorders with EDS. Therefore, we sought to compare clinical outcomes of patients presenting EDS. METHODS:A retrospective observational study was performed in...

journal_title：Acta neurologica Scandinavica

authors： Kim T,Lee JH,Lee CS,Yoon IY

更新日期：2016-07-01 00:00:00

abstract：INTRODUCTION:Charcot-Marie-Tooth disease (CMT) is a heterogeneous inherited neuropathy. The number of known CMT genes is rapidly increasing mainly due to next-generation sequencing technology, at present more than 70 CMT-associated genes are known. We investigated whether variants in the DCTN2 could cause CMT. MATERIA...

journal_title：Acta neurologica Scandinavica

authors： Braathen GJ,Høyer H,Busk ØL,Tveten K,Skjelbred CF,Russell MB

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:We set to investigate the possible role of genes and environment in developing Alzheimer's disease (AD) in monozygotic twin pairs discordant for AD. METHODS:Three pairs of twins discordant for AD, who were enrolled in the Finnish Twin Cohort, were used in the study and compared with 13 controls. Gray matter...

journal_title：Acta neurologica Scandinavica

authors： Rossi R,Pievani M,Järvenpää T,Testa C,Koskenvuo M,Räihä I,Kaprio J,Frisoni GB,Rinne JO,Laakso MP

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:To describe spinal epidural abscess after treatment with rituximab. METHODS:Report of a new case of cervical epidural spinal abscess after treatment with rituximab and review of the literature. RESULTS:Biologic agents are associated with an increased risk of serious infections, there are only few reports of...

journal_title：Acta neurologica Scandinavica

authors： Avila JD,Živković S

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:Multiple sclerosis (MS), Parkinson's disease (PD) and stroke (ST) subjects show balance impairments due to damage of the balance control system. The objective of the study was to assess the impact of MS, PD and ST on upright posture in eyes open condition and when visual and/or proprioceptive inputs are alter...

journal_title：Acta neurologica Scandinavica

authors： Cattaneo D,Carpinella I,Aprile I,Prosperini L,Montesano A,Jonsdottir J

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVES:Mutations in the CHCHD10 gene, which encodes a mitochondrially targeted protein, have emerged as an important cause of motor neuron disease and frontotemporal lobar degeneration. The aim of this study was to assess the clinical variability in a large family carrying the p.Gly66Val mutation of the CHCHD10 gen...

journal_title：Acta neurologica Scandinavica

authors： Pasanen P,Myllykangas L,Pöyhönen M,Kiuru-Enari S,Tienari PJ,Laaksovirta H,Toppila J,Ylikallio E,Tyynismaa H,Auranen M

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Paraneoplastic neurological syndromes (PNS) are rare remote effect of cancer. The antibodies and tumors associated with PNS have been well described, but there are still many clinically suspected cases in which no tumor or antibody can be identified. This is the first report of PNS showing hot cross-bun sign...

journal_title：Acta neurologica Scandinavica

authors： Ishikawa H,Kawada N,Taniguchi A,Odachi K,Mizutani A,Asahi M,Tomimoto H

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:It has been suggested that polymorphisms in the WT1 gene modulate the effect of IFN-β treatment in multiple sclerosis (MS) through regulation of the relationship between IFN-β and vitamin D. OBJECTIVE:To examine whether WT1 modulates the relationship between IFN-β and vitamin D in a longitudinal study with ...

journal_title：Acta neurologica Scandinavica

authors： Holmøy T,Esbensen QY,Torkildsen Ø,Wergeland S,Bjerve KS,Beiske AG,Midgard R,Šaltytė-Benth J,Hovdal H,Myhr KM

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:We evaluated the differences in brain morphology among patients with juvenile myoclonic epilepsy according to the occurrence of absence seizures. MATERIALS AND METHODS:Twenty-one juvenile myoclonic epilepsy patients with (n = 6) and without (n = 15) absence seizures were enrolled. We analyzed whole-brain T1-...

journal_title：Acta neurologica Scandinavica

authors： Park KM,Kim TH,Han YH,Mun CW,Shin KJ,Ha SY,Park JS,Kim SE

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to determine whether reactivation of Epstein-Barr (EBV) or activation of the anti-EBV immune response correlates with MS disease activity on MR imaging. METHODS:Subjects with early, active relapsing-remitting MS were studied for 16 weeks with blood and saliva samples collected...

journal_title：Acta neurologica Scandinavica

authors： Latham LB,Lee MJ,Lincoln JA,Ji N,Forsthuber TG,Lindsey JW

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:Stimulation of the subthalamic nucleus (STN-DBS) is an established treatment with long-term beneficial effects on motor symptoms in patients with Parkinson's disease (PD). The long-term development of non-motor problems after STN-DBS is not fully understood. In this study, we have studied how non-motor probl...

journal_title：Acta neurologica Scandinavica

authors： Lilleeng B,Gjerstad M,Baardsen R,Dalen I,Larsen JP

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the psychometric properties of the General Self-Efficacy Scale (GSE) in people with Parkinson's disease (PD). More specifically, we investigated data completeness, scaling assumptions, targeting, reliability, and construct validity. MATERIALS AND METHODS:This study involves da...

journal_title：Acta neurologica Scandinavica

authors： Nilsson MH,Hagell P,Iwarsson S

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Comprehensive epidemiologic data for multiple sclerosis (MS) in Spain are limited. The aim of this study was to collect epidemiologic data on MS in the Northern Seville District of Spain. MATERIALS AND METHODS:This longitudinal study identified possible MS cases every year from nine centres between 1 Januar...

journal_title：Acta neurologica Scandinavica

authors： Izquierdo G,Venegas A,Sanabria C,Navarro G

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Presence of mild cognitive impairment (MCI) as a predictor for Parkinson's disease dementia (PDD) has been discussed from a clinical perspective. Recently, a Movement Disorder Society (MDS) commissioned Task Force published guidelines for PD-MCI. However, long-term follow-ups of the PD-MCI guidelines for the...

journal_title：Acta neurologica Scandinavica

authors： Domellöf ME,Ekman U,Forsgren L,Elgh E

更新日期：2015-08-01 00:00:00

abstract：:Variants in the EIF4G1 gene have been recently identified to be responsible for autosomal dominant PD (PARK18), but its role in the PD-related neurodegeneration is unclear. Several EIF4G1 mutation/variants were found to be associated with PD, and functional studies have suggested that these variants may impair the abi...

journal_title：Acta neurologica Scandinavica

authors： Deng H,Wu Y,Jankovic J

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVES:Myotonic dystrophy type 1 (DM1) is the most common adult-onset muscular dystrophy. It is associated with motor symptoms but patients also display non-motor symptoms such as particular personality traits. Studies have reported mixed results about personality characteristics which may be attributable to small ...

journal_title：Acta neurologica Scandinavica

authors： Bertrand JA,Jean S,Laberge L,Gagnon C,Mathieu J,Gagnon JF,Richer L

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVES:To address the relationship between years lived with a disability (YLDs), prevalence and cost of neurological diseases, and to test whether there is a European North-South gradient for national health expenditure, disability, costs and prevalence of neurological diseases. MATERIALS AND METHODS:Information o...

journal_title：Acta neurologica Scandinavica

authors： Raggi A,Leonardi M

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Persons with multiple sclerosis (MS) engage in substantially less overall physical activity than healthy controls, but there is little information on public health rates of physical activity necessary for health benefits. PURPOSE:This study examined the rates of insufficient, moderate, and sufficient physic...

journal_title：Acta neurologica Scandinavica

authors： Motl RW,McAuley E,Sandroff BM,Hubbard EA

更新日期：2015-06-01 00:00:00

abstract：:Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder. AD is the most common cause of dementia worldwide, and its incidence is increasing in line with population aging. The primary feature of AD is progressive cognitive decline, and severe AD is characterized by reduced communication s...

journal_title：Acta neurologica Scandinavica

authors： Lee JH,Jeong SK,Kim BC,Park KW,Dash A

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the existence of polyautoimmunity in a Greek cohort of multiple sclerosis (MS), particularly multiple autoimmune syndrome (MAS), i.e., the presence of three or more distinct autoimmune disorders (ADs) in the same individual. METHODS:Cross-sectional control study. RESULTS...

journal_title：Acta neurologica Scandinavica

authors： Deretzi G,Kountouras J,Polyzos SA,Koutlas E,Pelidou SH,Xeromerisiou G,Zavos C,Tsiptsios I

更新日期：2015-04-01 00:00:00

abstract：:Patients with acute severe headache may have a secondary form of headache. Standard head computer tomography (CT) and cerebrospinal fluid (CSF) examination are often performed in the absence of neurological deficits to exclude subarachnoid hemorrhage (SAH). Increasingly, patients undergo subsequent CT angiography (CTA...

journal_title：Acta neurologica Scandinavica

authors： Alons IM,van den Wijngaard IR,Verheul RJ,Lycklama à Nijeholt G,Wermer MJ,Algra A,Jellema K

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to estimate the risk of hip fracture after first-ever stroke, using a nationwide population-base data set and a retrospective cohort design. MATERIALS AND METHODS:The cohort study involved 18,413 patients surviving a first-ever stroke during the 12-year period from 1997 to 2008. Ano...

journal_title：Acta neurologica Scandinavica

authors： Lin HL,Lin HC,Tseng YF,Liao HH,Worly JA,Pan CY,Hsu CY

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Fatigue and apathy are two of the most common and most disabling non-motor symptoms of Parkinson's disease (PD). They have a high coincidence and can often be confused; moreover, their relationship is not fully understood. The aim of our study was to describe the coincidence of apathy with different fatigue ...

journal_title：Acta neurologica Scandinavica

authors： Skorvanek M,Gdovinova Z,Rosenberger J,Saeedian RG,Nagyova I,Groothoff JW,van Dijk JP

更新日期：2015-02-01 00:00:00

abstract：:In the present review, we discuss observational and experimental data suggesting a protective effect from sun exposure and/or vitamin D in multiple sclerosis (MS). These data include geographic variations in MS occurrence, temporal trends, genetics, biobank, and questionnaire data. We look more closely at the differen...

journal_title：Acta neurologica Scandinavica

authors： Sundström P,Salzer J

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Both pregnancy and high vitamin D concentration seem to generate a protective environment against multiple sclerosis (MS) relapses. Longitudinal case-control analysis of vitamin D concentrations during pregnancy and lactation of MS mothers is lacking. AIMS OF THE STUDY:To examine serum 25-hydroxyvitamin-D3 ...

journal_title：Acta neurologica Scandinavica

authors： Jalkanen A,Kauko T,Turpeinen U,Hämäläinen E,Airas L

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Recognition of stroke symptoms and activation of emergency services are essential in minimizing delay for acute stroke treatments. In this study, we assessed public stroke awareness in Sweden. METHODS:One thousand and five hundred residents aged 18-79 years participated in a telephone survey. Open-...

journal_title：Acta neurologica Scandinavica

authors： Nordanstig A,Jood K,Rosengren L

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:To investigate efficacy and safety of entacapone across phase III studies in Parkinson's disease (PD) with wearing-off symptoms. METHODS:Retrospective, pooled analysis of four phase 3 randomized, double-blind, placebo-controlled studies with entacapone. RESULTS:475 of 808 patients with PD received entacapo...

journal_title：Acta neurologica Scandinavica

authors： Kuoppamäki M,Vahteristo M,Ellmén J,Kieburtz K

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Idiopathic Parkinson's disease (IPD) is characterized by the clinical motor symptoms of hypokinesia, rigidity, and tremor. Apart from these motor symptoms, cognitive deficits often occur in IPD. The positive effect of cholinesterase inhibitors on cognitive deficits in IPD and findings of earlier molecular im...

journal_title：Acta neurologica Scandinavica

authors： Lorenz R,Samnick S,Dillmann U,Schiller M,Ong MF,Faßbender K,Buck A,Spiegel J

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:The goal of this study was to evaluate the incidence of urological malignancies in MS patients using active screening. MATERIAL AND METHODS:A total of 495 MS patients (141 men, 354 women, age of 42±13.4) were included in the study. The duration of disease was 12.3±11 years, and the EDSS score was 4.3 (±2.5)...

journal_title：Acta neurologica Scandinavica

authors： Krhut J,Hradilek P,Nemec D,Tvrdik J,Zapletalova O,Zvara P

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that white matter lesions (WMLs) is an important risk factor for cognitive impairment, but the underlying mechanisms have not been clarified. OBJECTIVE:We tested the hypothesis that the cognitive impairments associated with periventricular white matter hyperintensities (PWMHs) on...

journal_title：Acta neurologica Scandinavica

authors： Zi W,Duan D,Zheng J

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The epidemiology, diagnosis, and treatment of motor neuron disease (MND) in Chinese patients are ill known. METHODS:A registered study of 461 MND patients was conducted across 10 facilities in 7 Chinese cities from February 2009 to March 2010. RESULTS:Patients were classified as amyotrophic lateral scleros...

journal_title：Acta neurologica Scandinavica

authors： Cui F,Liu M,Chen Y,Huang X,Cui L,Fan D,Pu C,Lu J,Zhou D,Zhang C,Yan C,Li C,Ding X,Liu Y,Li X,Jiang Y,Zhang J,Shang H,Yao X,Ding Y,Niu Q,Wang L

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:For patients with medication refractory medial temporal lobe epilepsy (MTLE), surgery offers the hope of a cure. However, up to 30% of patients with MTLE continue to experience disabling seizures after surgery. The reasons why some patients do not achieve seizure freedom are poorly understood. A promising the...

journal_title：Acta neurologica Scandinavica

authors： Breedlove J,Nesland T,Vandergrift WA 3rd,Betting LE,Bonilha L

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to examine the association between the frequency of alcohol consumption and stroke mortality among eastern Finnish men. MATERIAL AND METHODS:This study is a population-based sample of men with an average follow-up of 20.2 years. A total of 2609 men with no history of stroke at ...

journal_title：Acta neurologica Scandinavica

authors： Rantakömi SH,Kurl S,Sivenius J,Kauhanen J,Laukkanen JA

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:Epstein-Barr virus (EBV) infection is associated with multiple sclerosis (MS), and EBV may transform lymphoblastoid cell lines more frequently in MS patients than controls, but it is not clear whether this reflects a higher viral load or an enhanced ability to reactivate EBV. MATERIAL AND METHODS:MS patient...

journal_title：Acta neurologica Scandinavica

authors： Tørring C,Andreasen C,Gehr N,Bjerg L,Petersen T,Höllsberg P

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of caudal zona incerta-deep brain stimulation (cZi-DBS) on word-level speech intelligibility in patients with Parkinson's disease, under both an optimal listening condition and a simulated more naturalistic listening condition. MATERIALS AND METHODS:Spoken single words were extract...

journal_title：Acta neurologica Scandinavica

authors： Johansson L,Möller S,Olofsson K,Linder J,Nordh E,Blomstedt P,van Doorn J,Karlsson F

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Some previous studies reported an independent association between uric acid and coronary artery disease, while little is known on the association among uric acid and carotid artery disease (CAD). To address this issue, we investigated the association between CAD and higher uric acid level because...

journal_title：Acta neurologica Scandinavica

authors： Kumral E,Karaman B,Orman M,Kabaroglu C

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Major neurological improvement (MNI) at 24 hours represents a marker of early recanalization in ischaemic stroke. Although low body temperature is considered neuroprotective in cerebral ischaemia, some studies have suggested that higher body temperature may promote clot lysis in the acute phase of ischaemic ...

journal_title：Acta neurologica Scandinavica

authors： Kvistad CE,Thomassen L,Waje-Andreassen U,Logallo N,Naess H

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:To compare intravenous phenytoin (PHT) and intravenous lacosamide (LCM) for treatment of status epilepticus after failure of the first and second drug. METHODS:We retrospectively identified patients from a large community hospital in northern Germany who had been diagnosed with SE between August 2008 and De...

journal_title：Acta neurologica Scandinavica

authors： Kellinghaus C,Berning S,Stögbauer F

更新日期：2014-05-01 00:00:00